Gandaprasarini

Botanical Name : Paederia foetida Linn.

Family : Rubiaceae.

Identification No.: SDACH/HG/106

Introduction :

This is an anti-inflammatory drug used in Ayurvedic.

Names in different Indian languages :

Hindi : Gandhaprasarani, Pasaran

Malayalam : Gandhaprasaarini, appinaari

Sanskrit : Gandhaprasaarini, somaraji

Tamil : Talanili, Mudiyar Kundal.

Telugu : Takkeda

Folk : Gandhabhaaduli

Synonyms :

गन्धप्रसारिणी चैव प्रसारिण्यपि कीर्तिता |कटूष्णा दीपनी हृद्या वातकफविनाशिनी ||

Gañdhãdhyã, Balyã, Rãjabalã, Sarani

Classification according to Charak, Sushruta, Vagbhata & Bhav prakash:

Charak – Not mentioned

Sushruta – Not mentioned

Vagbhata – Not mentioned

Bhav Prakash – Haritakyadi Varga

Varieties & adulterants – (CV – controversy, AD – adulterants) :

1. Merremia tridentate  – [CV]

2. Laptadenia spartium – [CV]

3. Convolvulus arvenis – [CV]

4. P. scandens [CV]

5. Prasarani – CV (north Indians calls)

Morphology :

Glabrous or twining shrub.

Leaves simple, opposite ovate or lanceolate, acute or cuspidate; 6-8 cm x 2.5- 3.5 cm; petioles 2-3 cm long.

Flowers- in panicles, 15 cm long, violet coloured flowers.

Fruit- orbicular, wings pale, 1.0 cm. across.

Distribution & Habitat :

Central and Eastern Himalayan ranges, West Bengal.

Chemical constituents :

iridoid glycosides, sitosterol, stigmasterol, campesterol, ursolic acid, hentriacontane, hentriacontanol, ceryl alcohol, palmitic acid and methyl mercaptan (foul smell)

Properties :

Rasa Tikta

Guna Guru, Sara

Virya Usna

Vipaka Katu

Karma : vrishya,keshya, kandudhna, kushtaghna

carminative, antiinflammatory, astringent, spasmolytic, antidiarrhoeal, diuretic, antilithic

Indication :

Vãta Vyãdhi, Amavãta, Mütrakrcchra

rheumatic infections, piles,cough, inflammations of the liver, spleen

Part used :

Root, leaf

Dosage :

Leaf juice 10-15 ml

Powder 2-4 g

Decoction 50-100 ml

External use :

Analgesic. anti-inflammatory. Therefore it is used in all the vata disorders. It is the best medicine for it

Internal uses :

Digestive system : It is an antiflatulent and mild laxative. So it is used in abdominal pain, flatulence and constipation with hard stool. Cooked leaves or the warm paste of leaves is given in abdominal pain.

Circulatory system : It purifies the blood by its tikta rasa and alleviates vata by its ushna veerya. Therefore it is used in vatarakta.

Reproductive system : Aphrodisiac by guru property. So used in infertility.

Therapeutic Uses :

(1) Amavãta— Prasãriñi decoction, jaggary and Lasuna are fermented together for 7 days and then given orally with Pañchakola curna (C.D.)

(2) Mutrakrichra— Prasãrini paste is taken with coconut water (V.M.)

Research updates (past 5 years):

1. Study on anti-inflammatory activity in rodent models – [Journal Name, Year]

2. Phytochemical analysis indicating antioxidant potential – [Journal Name, Year]

3. Clinical evaluation in joint disorders – [Journal Name, Year]

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