Vruddhdaru

Botanical Name : Argyria nervosa

Family : Convolvulaceae

Identification No.- SDACH/HG/172

Introduction :

In Indian medicine, A. speciosa is not used as a single drug for sexual disorders in men, but as a supporting drug for exerting its antiphlogistic, spasmolytic and hypotensive actions on the central nervous system. The drug, in itself, did not show anaboliccum androgen-like or spermogenetic activity experimentally

Latin name: Argyria = lower surface of the leaf is silvery white in colour; speciosa = showy, splendid, handsome

Names in different Indian languages :

English : Elephant Creeper,woolly morning glory,

Hindi : Samurasos

Kannada : Candrapada

Malayalam : Samudrapacca,marikunni,marututari

Sanskrit : Vrddhadarukah,bastantri

Tamil : Samuttirappaccai,Ambgar

Telugu : Candrapada

Unani : Samunder sokh.

Folk : Bidhaaraa

Synonyms :

वृद्धदारुक आवेगी छागान्त्री वृष्यगन्धिका । वृद्धद्वारुः कषायोष्णः कटुस्तिक्तो रसायनः ॥१॥ वृष्यो वातामवातार्शः शोथमेहकफप्रणुत् । शुक्रायुर्बलमेधाऽग्निस्वरकान्तिकरः सरः ॥२॥

Vriddhadaaruka, Vriddhadaaru, Vriddhadaaraka, Bastaantri, Sthavira, Sthaviradaaru, Atarunadaaru, Samudrashosha.

Argyreia Nervosa (Burm.f.) Bojer

Varieties & adulterants – (CV – controversy, AD – adulterants) :

Seeds of Salvia plebeia R. Br. Are also known as Samudrashosha.

Ipomoea petaloidea Chois and Ipomoea biloba Forsk of the Convolvulacae family are also used as Vriddhadaaru

Morphology :

This widely spreading creeper has a stalk which is hard, thick, round and bears cotton wool.

Leaves – large, 20 – 30 cm. simple,oblong, pointed, upper surface is oily while the lower surface shows hairy growth.

Flowers – bell shaped, white from outside and violet or red within. Flowers bloom in the night and are fragrant.

Fruits—globose, oval, 2-4 cm. long, green, self breaking on ripening.

Flowering season – 4 months from rainy season, followed by fruiting This creeper is usually planted in gardens.

Chemical constituents :

Hallucinogenic -ergoline alkaloids (ergine and isoergine), sitosterol , antiphlogistic

Properties :

Guna: Snigdha

Rasa: katu,tikta,kashaya

Vipaka : Madhura

Virya: ushna

Karma – kaphavatashamak,kasaghna,hridya, sukra vardhana,arsoghna

External uses :

Application of the leaves is done as an anti-inflammatory and wound healing. An interesting point to note is that when the lower hairy surf the leaf is applied on the inflamed part, it accelerates suppuration while the upper smooth surface helps in wound healing.

Internal uses :

It is used in vata diseases, heart diseases, cough (bronchitis), hoarseness of voice, diabetes mellitus, sexual weakness, tuberculosis and emaciation.

Nervous system : Hallucinogen

Reproductive system : Increase sperm mobility

Indication :

Tuberculosis, cough, obesity, syphilis, cerebral disorder

Root—aphrodisiac (considered as a rejuvenator), nervine (used in diseases of nervous system, sexual disorders), diuretic (used in strangury), antirheumatic.

Seeds—hypotensive, spasmolytic.

Leaves—used externally in skin diseases (ringworm, eczema, boils,swellings); rubefacient, topicallystimulant.

Part used :

Root and seed

Dosage :

Root and bark powder 3 gm.; seed powder – 1/2 to 3/4 gm.

Therapeutic Uses :

ghritha prepared by this plant useful in piles as anuvasana vashthi

Yoga/Formulations: Vruddhadaruka kalpa, nagaradi modaka, vruddhadaru kusuma kalpa, Bahusala guda, Laxmivilasa rasa Kasa, Vriddhadaraka sama churna

IUCN Status: Not Evaluated

Research updates-

1) Anti- anxiety activity: Aim of the present study was a comparative evaluation of antianxiety activity of three traditionally used medicinal plants – Argyreia speciosa (Roots), Caesalpinia digyna (Roots) and Sphaeranthus indicus (Flowers). The activity of various extracts (petroleum ether, chloroform, ethanol and water) of all the three plants was evaluated using an elevated plus-maze model. The studies were conducted on lacca mice, and the test materials were administered per oral route. Results indicate that the ethanol extract of C. digyna roots exhibited maximum and significant dose dependent effect at 200 and 400 mg/kg on elevated plus-maze, the results were comparable to the standard antianxiety drug diazepam (2 mg/kg).

2) Anti-inflammatory action: The study was carried out using male albino mice (20-25 gm) and male wistar rats (100-150 gm). The ME was prepared using a soxhlet extraction process. The effect of ME of A. speciosa was investigated for analgesic activity using acetic acid-induced abdominal constriction, tail immersion method and hot plate method. The anti-inflammatory activity of ME of AS roots was studied using carrageenan-induced rat paw edema. The ME of A. speciosa showed significant analgesic and anti-inflammatory activity in mice and rats.

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